LOS ANGELES, July 20: Samyang Roundsquare announces the launch of Spindle, a science-led metabolic health brand with its debut product, Spindle Muscle+, to redefine how adults think about strength and aging. Spindle Muscle+ is powered by Akkermansia MYO™, a clinically studied strain shown to support muscle strength, through the gut.1
For decades, the conversation around muscle health has been limited to two directives: lift more and eat more protein. Spindle introduces a fundamentally new perspective. Emerging research reveals the gut-muscle connection: a critical driver in muscle health - regulating protein synthesis, systemic inflammation, and ultimately building and preserving muscle.2
Spindle Muscle+ is the first postbiotic supplement designed to support the gut-muscle connection.
"Maintaining muscle strength over time depends on more than protein and staying active alone," said Faissal Tahiri, Head of Healthcare, Samyang America. "With Spindle, we are bringing forward a science-led approach that looks at the biological systems influencing muscle function, including the growing scientific understanding of the gut–muscle connection."
The Silent Crisis: Muscle Loss Begins Earlier Than You Think
Muscle strength decline can begin as early as the mid-30s, progressing steadily with age. This loss impacts mobility, metabolic health and overall health span — the number of years spent living in good health. While most supplements focus on isolated nutrients such as protein or amino acids, few address the underlying biological systems that influence muscle function.
That's where Spindle starts.
The Science of Akkermansia MYO™
At the core of Spindle Muscle+ is Akkermansia MYO™, a pasteurized postbiotic derived from Akkermansia muciniphila - a beneficial microbe extensively studied for its role in gut barrier integrity and metabolic health.2 Notably, Akkermansia levels naturally decline with age.
Akkermansia MYO™ has undergone multiple rounds of research, testing, and clinical trials using the gold standard methodology (12-week, randomized, double-blind, placebo-controlled) for proving efficacy and safety. Recent clinical study in adults aged 60+, Akkermansia MYO™ resulted in:
- +10.4% increase in hamstring strength vs control3
- +14.1% increase in muscle power vs control3
- Significant increase in grip strength (+5.0% points vs control)3
- Significant increase in prealbumin levels – biomarker for muscle maintenance & repair (+5.6% points vs control)3
- Significant decrease in myostatin levels vs control – biomarker that limits muscle growth when elevated (−37.8% points)3
Designed For A New Generation of Longevity Thinkers
Spindle is built for health-invested adults, primarily in their 40s and 50s, who are thinking proactively about longevity, not waiting to react to decline.
- Skeptical of fragmented wellness solutions
- Motivated by science, not marketing claims
- Focused on staying capable for work, family, and life
Spindle Muscle+ is also suitable for adults using GLP-1 medications- a rapidly growing group facing increased risk of lean muscle loss during weight change, an underserved need in the supplement category.
Product Integrity Without Compromise
Spindle Muscle+ reflects rigorous standards in formulation and production:
- Gluten-free, non-GMO
- Free from common allergens
- No artificial sweeteners, color additives, or preservatives
- Produced in a GMP-certified facility under strict quality protocols
- Developed with an FDA-reviewed New Dietary Ingredient
Unlike traditional probiotics, Spindle Muscle+ leverages a heat-stabilized postbiotic to ensure shelf-stable potency and precision dosing for up to two years without refrigeration for convenient, consistent support.
Backed by Samyang Roundsquare
Spindle is developed by Samyang Roundsquare, a Korea-based, global food and healthcare company focused on science-led innovation and advanced nutrition.
"Muscle health is influenced by biological systems we're only beginning to fully understand, including the gut-muscle connection," said Ahjin Kim, PhD, Head of R&D, Samyang Healthcare . "The clinical research behind Akkermansia MYO™ gave us the evidence we needed to bring that science into a product people can trust. Spindle Muscle+ reflects our commitment to formulating from data, not assumptions."
