A Doctor’s Touch, Twice Blessed
Kochi, 16th April, 2025: Dr. Mathew Jacob was all smiles as he gently guided baby Shikha’s tiny fingers over the rice spread on a bronze plate, marking her Vidyarambham (first letter ceremony). As she traced her first letters, little did she know that the very man guiding her hand was the same one who, two years ago, had held it while giving her a second chance at life through a life-saving liver transplant. What unfolded at Aster Medcity was far more than a ritual, it was a heartfelt celebration of a mother’s hope, a grandmother’s selfless sacrifice, a father’s silent strength, and medical brilliance that brought it all together.
Baby Shikha Anillal, the second daughter of CRPF Jawan Anilal and Vineetha SP from Kayamkulam, began showing alarming signs just a month after her birth, yellowing of the eyes, pale stools, and abdominal swelling. The worried parents rushed her to SAT Hospital, Thiruvananthapuram, where she was diagnosed with Biliary Atresia, a rare and life-threatening liver disorder in infants. At only 69 days old, she underwent the Kasai procedure in an attempt to restore bile flow.
Though the surgery offered a temporary reprieve, her condition worsened over time due to recurring episodes of cholangitis. Seeking the best possible care, her family arrived at Aster Medcity, Kochi, where her case was attended by Dr. Geetha Mammayil, Pediatric Medical Gastroenterologist. Recognizing the complexities of Shikha’s illness, Dr. Geetha immediately referred her to Dr. Mathew Jacob, Senior Consultant, –Hepato Pancreato Biliary & Abdominal Multi Organ Transplant. After a comprehensive evaluation, the team led by Dr, Mathew Jacob concluded that a liver transplant was the only hope for Shikha’s survival.
Initially, Shikha’s mother volunteered; however, her pre-transplant assessment revealed medical limitations preventing her from proceeding as a donor. This was when her maternal grandmother, Mrs. Prasanna Kumari, volunteered to donate a part of her liver—even though she had an incompatible blood type. With immense resolve and love, she underwent exhaustive testing and was ultimately found fit to donate.
On May 20, 2023, at just nine months old, Shikha underwent a live donor liver transplant at Aster Medcity. Shikha’s post-operative course was smooth, and she was discharged after 23 days, ready to embrace life anew.
“This is truly a blessed moment. It’s a reminder of what science and love, can achieve in transforming lives,” said Dr. Mathew Jacob, Senior Consultant –Hepato Pancreato Biliary & Abdominal Multi Organ Transplant.
The family living in Coimbatore came down to Aster Medcity for baby Shikha’s Vidyarambham ceremony as it their wish to have their daughter’s learning journey ceremonially begin under the guidance of Dr. Mathew Jacob.
Following the Vidyarambham, Dr. Mathew Jacob presented Gurudakshina to Shikha, marking the significance of the moment for both doctor and patient. Interestingly, the ceremony coincided with the birthday of Mrs. Prasanna Kumari, Shikha’s maternal grandmother and liver donor, and a small celebration was held at the Aster Medcity campus to mark the occasion, including a cake-cutting in her honour.
Aster Medcity CEO Dr. Nalanda Jayadev and Dr. Mathew Jacob also handed over ‘Vishu Kaineettam’-a traditional token of blessing and prosperity, to Shikha and her sister as part of the New Year custom.
The event was attended by members of Shikha’s family, along with doctors, nurses, and other staff of Aster Medcity.
Chiara Bonini Receives DKMS Mechtild Harf Science Award for Innovation
Mumbai, APRIL 14, 2025: DKMS Stiftung Leben Spenden honored Professor Chiara Bonini, a pioneer in the clinical application of genetically modified T cells in stem cell transplantation, with the DKMS Mechtild Harf Science Award 2025. The award honors the outstanding achievements of internationally renowned physicians and scientists in the field of stem cell transplantation and cellular therapies.
“Professor Chiara Bonini’s groundbreaking findings in the field of personalized immunotherapy with genetically modified T cells have been essential in advancing the treatment of blood cancer. These discoveries have led to novel therapeutic approaches and hold the potential for translation into treatments for other types of cancer,” explains Professor Dr. Katharina Fleischhauer, member of the DKMS Medical Council and Head of the Institute for Cell Therapy Research at Essen University Hospital, in recognition of this year’s award winner. Chiara Bonini, MD, Professor of Hematology at the University Vita-Salute San Raffaele and Head of the Department of Experimental Hematology at the IRCSS San Raffaele Scientific Institute, Milan, accepted the award on March 31st, 2025, surrounded by physicians and esteemed guests from around the world, at the annual conference of the European Society for Blood and Marrow Transplantation (EBMT) in Florence, Italy. At the ceremony, the highly coveted DKMS John Hansen Research Grant was awarded and the DKMS Special Grant was also allocated for the first time.
“Chiara Bonini is one of the highly renowned scientists worldwide in the field of cell and gene therapy to treat cancer. She has been a leader in the clinical use of genetically modified T cells in stem cell transplantation, laying the foundation for innovative, life-saving therapies” said Professor Dr. Fleischhauer at the presentation of the DKMS Mechtild Harf Science Award, which comes with 10,000 Euro (approximately 9.26 Lakh INR). “Her work contributed to the development of the first EMA-approved genetically engineered cell-based medicinal product for cancer patients, paving the way for a new era of precision medicine and transformative treatments for patients worldwide.”
Award for pioneering personalized immunotherapy with genetically modified T cells
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains one of the most effective treatments for patients with hematologic malignancies and can also cure other blood disorders including inborn genetic diseases of the hematopoietic system. Despite its therapeutic potential, there is a risk of acute graft-versus-host disease (GvHD), a significant complication that contributes to both morbidity and mortality. To manage GvHD caused by allogeneic donor T cells, various T-cell-manipulation strategies have been explored. Early approaches focused on suicide gene therapy to balance graft-versus-leukemia effect (GVL) and immune reconstitution while controlling GvHD. Lately, genetic modifications, including tumor-specific T cell receptors (TCRs) or chimeric antigen receptors (CARs), have been introduced to enhance T cell antitumor efficacy.
Through more than 20 years of research in gene and cell therapy, Professor Bonini played a key role in the emergence of this field and advanced one of the first therapy projects applied to HSCT: the suicide gene therapy approach tends to eliminate alloreactive T cells in case of GvHD while preserving them in the absence thereof. Her team has since expanded into the field of cancer immunotherapy, refining TCR and CAR gene transfer techniques. One of Bonini’s major breakthroughs is TCR gene editing, which permanently reprograms T cells for enhanced precision and persistence in targeting cancer cells. By selecting tumor-specific antigens and engineering T cells to express optimal tumor-targeting receptors, her work has transformed T cell therapies into living drugs, designed to seek and destroy cancer cells with high specificity. “We have the techniques and knowledge for gene editing. The next challenge is identifying the right combinations of TCR and tumor specific antigen that will lead to the most effective therapies,” Bonini explains. Through further research, Bonini and her team were able to transfer this knowledge also to solid tumors: “Our aim is to create a TCR approach that could be utilized to generate TCR-edited cell products for a variety of cancer types. Since progress in cell therapies for solid tumors has been slower, this could be a game changer in this field,” says Bonini, who also serves on the executive committees of various scientific societies of cell and gene therapy, hematology and stem cell transplantation including ASGCT, ESGCT, EHA and EBMT.
On top: Research grants support next-generation scientists
During the ceremony, four outstanding fellows were also announced as the recipients of the DKMS John Hansen Research Grant 2025 Gabriele Casirati, MD, PhD (Boston Children’s Hospital, Boston, USA), Susan E. De Wolf, MD (Memorial Sloan Kettering Cancer Center, New York, USA), Stephen Persaud, MD, PhD (Washington University School of Medicine, St. Louis, USA), and Abdur Rehman, PhD (The University of Texas MD Anderson Cancer Center, Houston, USA).
Their research spans key areas such as T cell and leukemic blast interactions in the regulation of GVL, association of gut microbiome and CAR-T outcomes, and next-generation conditioning regimes with reduced toxicity for HSCT. “Supporting young medical and scientific talents in blood cancer research is an investment in the advancement of medicine,” emphasized Professor Dr. Marcel van den Brink, Chair of the DKMS Medical Council.
For the first time, DKMS also awarded the DKMS Special Grant, reinforcing the organization’s commitment to improve cancer care worldwide. Dr. Brigid McMillan, MBChB (Stellenbosch University, Stellenbosch, South Africa) committed herself to investigating and describing barriers to specialized hematological care in Southern Africa. This grant aims to support her research on improving cancer care in South Africa.
Understanding the nuances of Driver’s knee
By: Dr. J V Srinivas, Lead Consultant – Orthopaedics & Joint Replacement
Driver’s knee is a condition whereby a person experiences discomfort or pain in the knee joint as a result of the activity that he or she is performing, mainly by driving. It occurs primarily in the right knee since one keeps pressing the accelerator and brake pedals constantly, though sometimes the left knee may also be affected, especially for manual transmission users.
Driver’s knee develops due to several factors. It includes repetitive motion from continuous use of the accelerator and brake, which strains the knee joint. Poor seating alignment forces unnatural knee movements also can be one of the causes while prolonged driving with limited movement can stiffen the joint and cause discomfort. Additionally, underlying conditions like arthritis or patellar tracking problems can exacerbate the pain, making it more challenging to manage.
If left untreated, driver’s knee can lead to chronic pain that disrupts daily activities, reduced mobility due to stiffness or swelling, and inflammation such as tendonitis or irritation in the knee joint. Over time, it may also cause muscle imbalances, with certain muscle groups around the knee becoming weak or overused, further aggravating the condition.
A driver’s knee requires a combination of ergonomic adjustments, preventive measures, and targeted interventions. Proper seat positioning is fundamental; we as doctors recommend ensuring the seat is adjusted so the knees remain slightly bent and the feet can comfortably reach the pedals, reducing undue stress on the joint. Frequent breaks during long drives are equally important. Physicians advise stopping every two hours to stretch and move around, promoting blood circulation and preventing joint stiffness. Using lumbar or seat cushions can support proper posture, which minimizes strain on the knee and surrounding muscles. The role of knee exercises in strengthening the joint and enhancing flexibility is important; routines such as leg lifts and hamstring stretches are particularly beneficial in stabilizing the knee. For patients experiencing pain, over-the-counter pain relievers or anti-inflammatory medications can provide temporary relief, but they should be used judiciously and under medical guidance. A holistic approach combining these measures can significantly alleviate symptoms and improve long-term joint health.
Yes, driver’s knee can resolve with proper care and preventive measures. Addressing the underlying cause, modifying driving habits, and incorporating exercises to strengthen the knee often lead to full recovery. However, if symptoms persist, consult a healthcare professional.
To achieve optimal driving posture and prevent discomfort such as driver’s knee, it is crucial to focus on seat and body positioning. Adjusting the seat height so that the hips are slightly higher than the knees promote proper alignment and reduces pressure on the lower body. The distance from the seat to the pedals should allow for a comfortable reach, ensuring the legs remain slightly flexed without overextension, which can strain the knees. Back support is equally important; using the seat’s built-in lumbar support helps maintain the spine’s natural curvature, preventing back strain that can indirectly affect knee posture. Additionally, resting the feet flat on the floor when not engaging the pedals provides stability and prevents unnecessary tension in the legs. Lastly, the steering wheel should be positioned close enough to allow a relaxed grip without requiring the shoulders or arms to stretch, minimizing fatigue and maintaining overall ergonomic alignment. Together, these adjustments ensure a comfortable and health-conscious driving experience. Adopting these positions minimizes knee strain and promotes comfort during driving
First-of-its-Kind Two-Level Lumbar Disc Replacement Surgery Explained
Greater Noida, 10 April, 2025: Fortis Hospital, Greater Noida, has achieved a historic medical milestone. For the first time in Uttar Pradesh—and for the first time within the Fortis Healthcare Group—a highly complex and rare two-level lumbar disc replacement surgery has been successfully performed by the hospital’s expert team. The rare procedure was carried out on Harpal Singh, a former Indian national medal-winning athlete, who has now fully recovered.
This type of surgery is considered rare globally. According to statistics, lumbar disc replacement accounts for less than 1% of all spine surgeries, and two-level lumbar disc replacement is performed in less than 0.1% of cases worldwide. Until now, only four medical centres in India have executed this complex procedure, with only three hospitals in the Delhi-NCR region being capable of performing it.
The challenging surgery was led by Dr Himanshu Tyagi (Head, Spine and Orthopaedic Surgery), along with Dr Mohit Sharma and Dr Rajesh Mishra. Crucial support was provided by Dr Bhoop Singh (Head, Anaesthesia), Dr Jagdish Chander (Head, Surgery Department), and an experienced vascular surgeon.
41-year-old Harpal Singh had been suffering from chronic lower back pain for several years. Despite undergoing a spine surgery in 2007, his condition deteriorated. Upon re-evaluation, disc degeneration at the L4-5 and L5-S1 levels and spinal instability at the L3-4 level were diagnosed. Considering his relatively young age and active lifestyle, the medical team decided to proceed with spinal fusion at L3-4 and artificial disc replacement at L4-5 and L5-S1.
Dr Himanshu Tyagi explained that the surgery was conducted in two stages using an anterior approach, a technique considered highly complex. This method involves risks to major blood vessels, abdominal organs, and nerves, potentially leading to internal bleeding, paralysis, or long-term disability. However, the experienced team at Fortis Greater Noida successfully carried out the surgery without any complications.
Post-surgery, Harpal Singh was able to walk the very next day and was discharged on the fourth day without any neurological issues. He can now walk independently and climb stairs with ease. The surgery has truly given him a new lease on life.
Speaking about this remarkable achievement,Dr. Praween Kumar, CEO & Facility Director, Fortis Hospital Greater Noida, said: “This groundbreaking achievement reflects the exceptional capabilities of our medical team and the advanced infrastructure at Fortis Greater Noida. Performing a two-level lumbar disc replacement with such precision is a rare feat, and we’re proud to bring this level of care to Uttar Pradesh for the very first time.”
Expressing his gratitude, Mr. Harpal Singh (Patient) shared:“I had almost lost hope after living with constant pain for so many years, I came all the way to India from Canada to get my treatment as the last resort. Thanks to the incredible doctors at Fortis Greater Noida, I feel like I’ve been given a second chance. Being able to walk pain-free again is nothing short of a miracle.”
This landmark success marks a significant milestone for the Fortis Healthcare Group and positions Fortis Greater Noida as an advanced centre for complex spine surgeries.
Mental Health Software Market Benefits from AI Integration
The mental health software market has been experiencing significant growth, fueled by the increasing demand for mental health services and technological advancements that enhance the way care is delivered. According to projections from Persistence Market Research, the market, valued at USD 5.76 Bn in 2023, is expected to surge to USD 28.35 Bn by the end of 2033, growing at a compound annual growth rate (CAGR) of 17.3% from 2023 to 2033. As mental health challenges continue to rise globally, AI integration in mental health software is playing a crucial role in driving this growth and improving mental health care.
This article will explore how AI integration is benefiting the mental health software market, driving innovations, and improving access to care.
The Mental Health Software Market: A Rapidly Expanding Industry
The demand for mental health services has been on the rise due to growing awareness of mental health conditions, the increased prevalence of mental illnesses, and the global push for better access to mental healthcare. The COVID-19 pandemic further intensified this demand, revealing gaps in the traditional mental health system and highlighting the need for more efficient, scalable solutions.
Mental health software encompasses a wide array of tools and technologies designed to assist in diagnosing, managing, and treating mental health conditions. These include telehealth platforms, electronic health records (EHR), therapy apps, AI-driven diagnostics, and predictive tools. As mental health awareness continues to grow and the stigma surrounding mental health diminishes, the demand for these solutions has escalated.
With the global mental health software market predicted to reach USD 28,348.7 million by 2033, AI integration is becoming one of the driving forces behind this exponential growth. The incorporation of AI into mental health software solutions is helping address critical challenges in mental healthcare, offering a more personalized, accessible, and efficient approach to care.
How AI Integration Transforms Mental Health Software
AI has proven to be transformative in several industries, and healthcare is no exception. In the mental health domain, AI tools are assisting providers, therapists, and patients in ways that were previously unimaginable. Here’s how AI integration is transforming the mental health software landscape:
a. Enhanced Diagnostics and Early Detection
AI-powered mental health software can analyze large datasets to identify patterns and predict the onset of mental health issues before they manifest in full force. Machine learning algorithms can analyze speech, text, and behavior patterns to detect early signs of mental health conditions such as depression, anxiety, and PTSD. This predictive capability allows for earlier intervention, potentially preventing the escalation of symptoms.
For example, natural language processing (NLP) tools can analyze the tone, pace, and content of speech or written communication to detect emotional distress, offering insights that human clinicians may miss. This results in more accurate diagnoses and enables healthcare providers to take proactive steps in managing patients’ conditions.
b. Personalized Treatment Plans
AI-driven mental health software is revolutionizing the way treatment plans are developed. By analyzing a patient’s history, preferences, and data gathered through apps or telehealth interactions, AI can create highly personalized treatment pathways that are better suited to individual needs.
Machine learning algorithms can suggest therapy techniques, medication regimens, and coping strategies that are tailored to the patient’s specific mental health profile. This not only improves the chances of successful outcomes but also helps streamline the treatment process, reducing the trial-and-error period that often accompanies mental health treatment.
c. Predictive Analytics for Improved Patient Management
Predictive analytics powered by AI can provide mental health professionals with insights into how patients are likely to respond to specific treatments. By analyzing past patient data, including response to medications and therapies, AI systems can predict future behavior and outcomes. This can guide clinicians in adjusting treatment plans, enhancing the effectiveness of mental health interventions.
For example, AI can forecast when a patient is most at risk of relapse, allowing for targeted interventions at the right time. This predictive capability is especially beneficial for patients with chronic mental health conditions, offering a proactive approach to care.
d. Access to Care: Telemedicine and Virtual Therapy
One of the most significant benefits of AI integration is its role in increasing access to mental health care. With the rise of telemedicine and virtual therapy, AI-powered mental health software enables patients to access care remotely, reducing barriers such as geographical location, long wait times, and the stigma associated with in-person therapy sessions.
AI-driven chatbots and virtual assistants can offer immediate support to individuals in distress, providing a first line of assistance for people who may be hesitant to seek human interaction. These AI-powered tools can offer coping strategies, mood tracking, and even guide users through mindfulness exercises. In the long run, this increases the scalability of mental health services and ensures that more individuals can receive the help they need.
e. Data-Driven Insights for Clinicians
AI integration is empowering clinicians with data-driven insights that allow for more informed decision-making. AI algorithms can analyze patient data, including mental health history, genetics, lifestyle factors, and even environmental variables, to identify potential triggers and risk factors for mental health conditions. This wealth of information enables healthcare providers to offer better-informed recommendations and make more accurate diagnoses.
Clinicians can leverage AI tools to identify patterns that may not be immediately apparent from traditional assessments. By integrating AI into their workflows, mental health professionals are better equipped to address the complex and evolving needs of their patients.
Benefits of AI in Mental Health Software
a. Improved Efficiency and Accuracy
One of the major advantages of AI integration in mental health software is the efficiency it brings to the mental healthcare process. By automating time-consuming tasks like data analysis and appointment scheduling, AI allows mental health professionals to focus more on patient care and less on administrative duties. AI also helps reduce human errors by offering more accurate assessments and diagnostic support, ultimately leading to better outcomes for patients.
b. Cost-Effective Solutions
AI-powered mental health tools have the potential to reduce healthcare costs significantly. By providing scalable solutions, such as virtual therapy, AI-based chatbots, and predictive analytics, healthcare providers can reduce the need for in-person consultations and expensive treatments. Moreover, AI can help identify cost-effective treatments and therapies that yield the best outcomes, optimizing resource allocation.
c. Increased Engagement and Adherence
AI-based tools can help keep patients engaged with their treatment plans. For example, mood-tracking apps, AI-powered journaling, and reminders for medication or therapy sessions help individuals stay on top of their mental health. This increased engagement, combined with personalized recommendations, enhances adherence to treatment plans, leading to better long-term results.
d. Reduced Stigma and Increased Accessibility
AI tools can also play a crucial role in reducing the stigma surrounding mental health care. Chatbots and virtual assistants provide anonymous, non-judgmental support, enabling individuals to seek help without fear of societal judgment. Furthermore, AI integration in mental health software breaks down barriers to care, such as geographical location or availability of healthcare professionals, by offering virtual and remote support.
Conclusion
The mental health software market is expanding rapidly, and AI integration is playing an instrumental role in its growth. By enhancing diagnostics, personalizing treatment plans, improving patient management, and increasing access to care, AI-powered solutions are transforming the mental healthcare landscape. As mental health awareness continues to rise and demand for services increases, AI-driven technologies will only become more vital in delivering efficient, effective, and accessible mental health care to a global population. The future of mental health care looks brighter, with AI poised to shape the industry for years to come.
As the mental health software market grows and evolves, the collaboration between AI and mental healthcare professionals promises to create a more comprehensive, supportive, and effective approach to managing mental health conditions, improving the lives of individuals worldwide.
Anytime Fitness Unveils India’s Inspiring Transformation Stories this World Health Day
New Delhi: Anytime Fitness is not just a gym – it is a revolution that has transformed hundreds of lives across the country. The survivors of accidents, cancer patients, obesity, heart patients, and many other health issues – Anytime Fitness has delivered more than a physical transformation – it has been an oasis of hope, willpower, and recommence.
This World Health Day, Anytime Fitness is celebrating by honouring real heroes whose inspiring stories were nurtured by the unwavering support of Anytime Fitness — individuals such as Viren Pratap Singh, Tamanna Punjabi, Aanchal Sehgal, and Kim.
In 2016, Viren’s life was irreversibly altered. Viren fell into a 45-day coma, on the support of the ventilator for 5 days. He couldn’t move, talk, or even identify the world he belonged to. For his family, it was a nightmare fight for his life —But the moment he stepped into Anytime Fitness, everything changed. With the aid of experts, and an encouraging set of people, Viren rebuilt his body and mind.
“I came broken, but I left transformed. I was Viren 2.0,” says Viren.
Tamanna Punjabi, a survivor of cancer, viewed fitness as her key to recovery. With the motivation of the gym and encouragement from her family, she defeated physical and emotional traumas. She inspires others today to look beyond and draw strength from weakness.
Aanchal Sehgal, a professional banker, discovered sport later in life. With a vision in her mind and Anytime Fitness by her side, she turned amateur athlete — proving it’s never too late to learn something new.
And then there’s Kim — an entrepreneur and powerlifter who embodies what it means to fight back. Punned by failure and self-doubt, Kim discovered her purpose in life through strength training.
“It’s never too late to take a stand and follow your dreams,” They says.
“At Anytime Fitness, we’ve had the privilege of being along for some of the most motivational rides — from Viren Pratap Singh, who fought death and came back stronger than ever after a near-fatal accident; to Tamanna Punjabi, who fought cancer and won; to Aanchal Sehgal, who became a sports Icon after rebirth as a banker; and Kim, a powerlifter and entrepreneur who broke boundaries through sheer will and determination. Each one of them is a testament to why we do what we do. Their resolve, grit, and refusal to give up are reflective of our community’s spirit. Anytime Fitness is not just a gym — it’s a support group, a sanctuary, and a launchpad for people willing to make a difference. We are privileged to be along with them on their motivational rides.” States, Mr. Vikas Jain, Managing Director, Anytime Fitness India
Whether weights or spirits need to be lifted, Anytime Fitness is where revolution truly begins. Because here, fitness is never about; it’s about transforming actual people into their absolute best, one life, one story, and one rep at a time.
MGM Healthcare Performs World’s First Modified Multi-Visceral Transplant
Mumbai / Chennai, April 5th, 2025: In a groundbreaking medical achievement, MGM Healthcare has successfully performed the World’s first modified multi-visceral transplant (MMVT) for the treatment of a rare intestinal disorder, saving the life of a 32-year-old patient from Kerala who had been suffering from bloody diarrhea, along with a severe drop in hemoglobin levels, progressive malnutrition, recurrent infections, and abdominal swelling.
His diagnosis, diffuse primary lymphangioma of the intestine, was a non-malignant intestinal condition. It was so extensive that conventional surgical approaches, such as bowel resection, were not viable. To address this, the expert surgical team at MGM Healthcare performed a modified multi-visceral transplant, replacing the stomach, pancreatico-duodenal complex (the pancreas and the first part of the small intestine), small intestine, and large intestine, with innovative modifications to enhance graft function and reduce immunologic risks. The patient is now recovering well, marking a major milestone in transplant medicine and offering new hope for those with complex intestinal disorders.
Before proceeding with the modified multi-visceral transplant (MMVT), the medical team at MGM Healthcare took critical steps to stabilise the patient. Given the severity of gastrointestinal bleeding caused by diffuse primary intestinal lymphangioma, the team performed an emergent subtotal enterectomy, which refers to the surgical removal of a significant portion of the diseased intestine to control the bleeding. The team also initiated total parenteral nutrition (TPN), a method of delivering essential nutrients intravenously, bypassing the digestive system altogether to ensure the patient’s nutritional stability. These interventions optimised the patient’s condition for the complex transplant procedure that followed.
The MMVT surgical intervention was headed by Prof. Dr. Anil Vaidya, M.D., Chair and Director of the Institute of Multi-Visceral and Abdominal Organ Transplant, along with Dr. Senthil Muthuraman, senior Consultant, Multi Visceral and abdominal organ transplant and Dr. Sivakumar Mahalingam, Senior Consultant, Surgical Oncology, Dr. Venkatesh B.S, Consultant Multi Visceral Transplant Program at MGM Healthcare. The anesthesia and intensive care team comprised Dr. Dinesh Babu, and Dr. Nivash Chandrasekaran.
In his comments, Prof. Dr. Anil Vaidya, said that the patient had an exceptionally high disease burden, with extensive involvement of the small intestine, making traditional surgical options like segmental resection ineffective. Given the severity of his condition, we needed an innovative approach to restore his digestive function and overall health. Our team decided to proceed with a modified multi-visceral transplant, replacing the stomach, pancreatico-duodenal complex, small intestine, and large intestine. We also made key modifications to improve graft function and reduce the risk of complications. I am truly delighted that the world’s first MMVT for this rare condition has been a success. The patient has now gone over two months without any signs of graft rejection or major complications, which is a remarkable outcome.”
In his comments, Dr. Senthil Muthuraman, said, “Primary intestinal lymphangioma is an exceptionally rare condition. The patient developed enteropathy, which led to chronic diarrhea, malabsorption of nutrients, and protein loss. The bloody diarrhea persisted for over a month and hemoglobin dropped to dangerous levels, requiring multiple blood transfusions. The extensive involvement of the small intestine made conventional treatments unfeasible. We first performed a subtotal enterectomy to control the bleeding and placed him on TPN to ensure he remained strong enough for the transplant. It is truly gratifying to see that he has made an excellent recovery, with no signs of graft rejection, resolution of enteropathy, and optimal graft function. This case marks a major breakthrough in transplant surgery, and we are proud to have been part of this life-saving procedure.”
Successful Surgical Removal of Lodged Denture at Wockhardt Hospitals, Mira Road
Mumbai: – In a remarkable surgical procedure, Dr. Chandra Veer Singh and his skilled medical team at Wockhardt Hospitals, Mira Road, successfully removed a lodged denture from the esophagus of a 74-year-old patient, Mrs. Sandhya Thakur (name changed). The complex surgery became necessary after an initial endoscopic removal attempt was unsuccessful due to deep embedding in the esophageal mucosa. Mrs. Sandhya Thakur arrived at the hospital experiencing severe difficulty in swallowing and discomfort for six days. A Gastrointestinal (GI) endoscopy confirmed that a denture was lodged just below the upper esophageal sphincter (UES). Attempts to extract it using endoscopic instruments such as rat-tooth forceps failed due to deep embedding, making surgical intervention essential.
A multidisciplinary surgical team from Wockhardt Hospitals, Mira Road, led by Dr. Chandraveer Singh Consultant Otorhinolaryngologist, Head & Neck Oncosurgeon, Dr. Tirathram Kaushik Consultant Oncosurgeon & Minimal Access Surgeon and Dr. Sheetal Radia Consultant Otorhinolaryngologist, Head & Neck Oncosurgeon performed an esophagostomy through a neck incision under general anesthesia. The foreign body was carefully removed en bloc, and the esophagus was repaired using 3-0 PDS sutures to ensure proper healing. Hemostasis was confirmed, and a surgical drain was placed before closing the incision in layers. Following the procedure, Mrs. Sandhya Thakur is in stable condition and under close monitoring for any post-operative complications, such as infection or swallowing difficulties.
Foreign body ingestion, particularly lodged dentures, is a significant medical concern among the elderly. If left untreated, it can result in perforation, infection, and life-threatening complications. This case underscores the expertise and precision of the surgical team at Wockhardt Hospitals, Mira Road who successfully managed this high-risk case with advanced surgical techniques. Wockhardt Hospitals, Mira Road, continues to uphold its commitment to advanced medical interventions and patient-centered care. The successful removal of the lodged denture reinforces the hospital’s reputation for handling complex cases with cutting-edge expertise and multidisciplinary collaboration.
Mrs Sandhya Thakur is expected to make a full recovery under the continued supervision of the medical team. This case highlights the importance of early diagnosis, timely intervention, and advanced medical facilities in ensuring successful patient outcomes.
5 Effects of Winter on Fertility A Guide to Couples Planning a Baby
By, Dr. Smrithi D Nayak, Consultant – Obstetrics & Gynaecology, Aster RV Hospital
Winter in India introduces a specific set of issues and opportunities for those who want to start or expand their families. Here’s how the cold time of the year may play with fertility, along with some tips to make the best of it:
1. Improved Fertility: Hormones in action during Winters
There are changes of hormones that happen normally at this time. Researchers have found that during the winter, levels ofluteinizing hormone (LH) and follicle-stimulating hormone (FSH) are made at a greater rate, thus bringing quality to ovulation and sperm. Most men notice a peak in testosterone during winter and women notice regularity of their cycles, increasing their chances of conceiving.
Pro Tip: Keep a close eye on ovulation during this time and have intercourse during your fertile window for maximum success.
2. Improved Sperm Quality in Men
The cooler temperatures are more favorable to sperm production and quality. Heat can damage sperm, but winter’s cooler climate maintains an ideal environment, thus boosting sperm count and motility.
Pro Tip: Advise your partner to avoid overly tight clothing and hot baths to maintain optimum sperm health throughout winter.
3. Seasonal Diet Boosts Fertility
Winter has plenty of fertility-enhancing foods, such as green leafy vegetables (spinach, fenugreek), fresh citrus fruits (oranges, guava), and nuts. These are rich in antioxidants, vitamins, and minerals needed to maintain the reproductive system. Foods like sesame seeds and jaggery are also taken as natural fertility enhancers in Indian traditional diets.
Pro Tip: Eat seasonal food in your everyday diet to boost your reproductive health and keep your hormones in check.
4. Less Stress and Improved Sleep
Winter’s longer nights tend to promote improved sleep, which is necessary for the balancing of hormones. Better quality of sleep would enhance the conditions for ovulation and sperm production, whereas decreased stress improves overall fertility.
Pro Tip: Establish a bedtime routine, enjoy warm beverages like herbal tea, and keep your bedroom cozy to maximize the benefits of winter’s restful nights.
5. Chances of Seasonal Diseases and Weight gain
On the other hand, cold weather may have the impact of increasing the vulnerability of acquiring colds and flu, and might thus weaken the body for some time, along with infertility. Also, minimal movement, calorie-rich foods are the factors that lead to gaining weight, which impacts hormone levels.
Pro Tip: Light exercises like yoga or walking, maintain healthy weight, and keep in your diet immunity-boosting foods like turmeric milk and ginger tea.
Final Thoughts for Couples Trying to Conceive
Winter is indeed the perfect time to focus on one’s reproductive health. But the right approach—healthy eating, stress management, and leveraging nature’s hormonal benefits—can definitely make the most of it. Stay warm, stay hopeful, and remember that this is a journey unique to each couple.